Since the beginning of plant GST research a massive amount of information has been gathered on the role of GSTs in various plant-pathogen interactions (reviewed earlier by Gullner and Komives, 2001, 2006)
The ideal dosage is 10-20 mg per kg of body weight, if there is excess skin damage like fine lines, dark spots, wrinkles and dark circles
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Morning doses work well, ideally 20-30 minutes before breakfast
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25 Note: Topical concentration for hyperpigmentation is typically 2%